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Publications

Individual publications by MRCCT Primary Members

Silvia Vidal / Philippe Gros / Mathieu Blanchette / Bastien Castagner / Ines Colmegna / Jorg Fritz / Samantha Gruenheid
Nada Jabado / David Langlais / Danielle Malo/Judith Mandl / Corinne Maurice / Ana Nijnik / Martin Olivier / Ciro Piccirillo Salman Qureshi / Rob Sladek / Maya Saleh / Don Vinh / Jerôme Waldispühl

Selected MRCCT Joint Publications

Publications
Lack of evidence for intergenerational inheritance of immune resistance to infections.
Kaufmann E, Landekic M, Downey J, Chronopoulos J, Teimouri Nezhad S, Tran K, Vinh DC, Barreiro LB, Divangahi M. Nat Immunol. 2022 Feb;23(2):203-207. PMID: 35058614
Unbiased immune profiling reveals a Natural Killer cell-peripheral nerve axis in fibromyalgia
Verma V, Drury G, Parisien M, Özdağ Acarli AN, Al-Aubodah T, Nijnik A, Wen X, Tugarinov N, Verner M, Klares R, Linton A, Krock E, Urbina CM, Winsvold B, Fritsche LG, Fors EA, Piccirillo C, Khoutorsky A, Svensson C, Fitzcharles MA, Ingelmo PM, Bernard N, Üçeyler N, Sommer C, King I, Meloto CB, Diatchenko L. Pain 2021 Sep 24. Online ahead of print: doi: 10.1097/j.pain.0000000000002498. PMID: 34913882
Safety and preliminary efficacy of allogeneic bone marrow-derived multipotent mesenchymal stromal cells for systemic sclerosis: a single-centre, open-label, dose-escalation, proof-of-concept, phase 1/2 study.
Farge D, Loisel S, Resche-Rigon M, Lansiaux P, Colmegna I, Langlais D, Charles C, Pugnet G, Thibault A, Maria J, Chatelus E, Martin T, Hachulla E, Kheav VD, Lambert NC, Wang HC, Michonneau D, Martinaud C, Sensebé L, Cras A, Tarte K (2022). The Lancet Rheumatology. (IF=8.1) In press https://doi.org/10.1016/S2665-9913(21)00326-X
The Role of Leishmania GP63 in Modulation of Innate Inflammatory Response to Leishmania major Infection.
Chan A, Ayala JM, Alvarez F, Piccirillo C, Dong G, Langlais D*, Olivier M* (2021). PLOS One. (IF=3.2) 16(12): e0262158. https://doi.org/10.1371/journal.pone.0262158 * Corresponding authors. PMID: 34972189
Pre-existing chromatin-accessibility and gene expression differences among naïve CD4+ T cells influence effector potential.
Rogers D, Sood A, Wang HC, van Beek JJP, Rademaker T, Artusa P, Schneider C, Shen C, Wong D, Lebel ME, Condotta SA, Richer MJ, Martins AJ, Tsang JS, Barreiro L, Francois P, Langlais D, Melichar HJ, Textor J, Mandl JN (2021). Cell Reports. (IF=9.4) 37:110064, doi.org/10.1016/j.celrep.2021.110064. (Featured on the cover of the issue). PMID: 34852223
The NF-κB Transcription Factor c-Rel Modulates Group 2 Innate Lymphoid Cell Effector Functions and Drives Allergic Airway Inflammation.
Mindt BC, Krisna SS, Duerr CU, Mancini M, Richer L, Vidal S, Gerondakis S, Langlais D, Fritz JH (2021). Frontiers in Immunology. (IF=5.1) 12:664218 https://doi.org/10.3389/fimmu.2021.664218 PMID: 34867937
Glutathione metabolism is a regulator of the acute inflammatory response of monocytes to (13)-ꞵ-D-Glucan.
Ramendra R, Mancini M, Ayala JM, Tung LT, Isnard S, Lin J, Routy JP, Nijnik A, Langlais D (2021) Frontiers in Immunology. (IF=5.1) 12:694152, doi.org/10.3389/fimmu.2021.694152. PMID: 34858388
The c-Rel transcription factor limits early interferon and neuroinflammatory responses to prevent herpes simplex encephalitis onset in mice.
Mancini M, Charbonneau B, Langlais D, Vidal SM (2021) Scientific Reports (IF=5.1) 11:21171, https://doi.org/10.1038/s41598-021-00391-7 PMID: 34707143
p53-Dependent Induction of P2X7 on Hematopoietic Stem and Progenitor Cells Regulates Hematopoietic Response to Genotoxic Stress.
Tung LZ, Wang HC, Belle JI, Petrov JC, Langlais D, Nijnik A (2021) Cell Death Disease (IF=8.5) 12:923. https://doi.org/10.1038/s41419-021-04202-9 PMID: 34625535
Regulation of B lymphocyte development by histone H2A deubiquitinase BAP1.
Lin YH, Liang Y, Wang HC, Tung LT, Forster M, Subramani PG, Di Noia JM, Clare S, Langlais D, Nijnik A. Frontiers in Immunology. 2021, 12:626418, https://doi.org/10.3389/fimmu.2021.626418. PMID: 33912157
A Loss-of-Function Mutation in the Integrin Alpha L (Itgal) Gene Contributes to Susceptibility to Salmonella enterica Serovar Typhimurium Infection in Collaborative Cross Strain CC042.
Zhang J, Teh M, Kim J, Eva MM, Cayrol R, Meade R, Nijnik A, Montagutelli X, Malo D, Jaubert J. Infect Immun. 2019 Dec 17;88(1):e00656-19. doi: 10.1128/IAI.00656-19. Print 2019 Dec 17. PMID: 31636138
The NF-kB transcription factor c-Rel modulates group 2 innate lymphoid cell effector functions and drives allergic airway inflammation.
Mindt B.C., Krisna S.S., Duerr C.U., Mancini M., Richer L., Vidal S.M., Gerondakis S., Langlais D., Fritz J.H.**. Frontiers in Immunology 12:664218 (2021) PMID: 34867937
Inherited human PD-1 deficiency underlies tuberculosis and autoimmunity.
Ogishi, M., Yang, R., Aytekin, C., Langlais, D., Khan, T., Rahman, M., Ali, FA., Delmonte, OM., Chrabieh, M., Zhang, P., Gruber, C., Pelham, S., Spaan, AN. Rosain, J., Béziat, V., Rapaport, F., Kerner, G., Drutman, S., Tezcan, I., Hosnut, FO., Dogu, F., Ikinciogullari, A., Williams, S., Emile, JF., Rozenberg, F., Glickman, MS., Bustamante, J., Rao, VK., Kainulainen, L., Vilarinho, S., Lifton, RP., Boisson, B., Abel, L., Bogunovic, D., Marr, N., Notarangelo, LD., Gros, P., Boisson-Dupuis, S. and Casanova, JL. Nature Medicine 27(9):1646-1654, 2021. PMID: 34183838
Inherited CD28 deficiency in otherwise healthy patients with disseminated warts and giant horns.
Béziat, V., Rapaport F., Jiafen Hu J., Titeux M., Bonnet des Claustres M., Griffin H., Louis DM., Bourgey M., Bandet E., Ma, CS., Sherkat R., Rokni-ZadehH., Changi-Ashtiani M., Delmonte OM., Toshiaki F., Habib T., Guenoun A., Khan T., Bendner N., Rahman M., About F., Yang R., Rao G., Rouzaud C., Li J., Shearer D., Balogh K., Dabiri S., Momenilandi M., Nammour J., Alyanakian MA., Leruez-Ville M., Guenat D., Materna M., Marcot L., Soret C., Vahidnezhad H., Youssefian L., Saeidian A., Uito J., Catherinot E., Navabi SS., Zarhate M., Woodley DT, Jeljeli M., Belkaya S., Lorenzo L., Rosain J., Bayat M., Lanternier F., Lortholary O., Blanche S., Zakavi F., Gros P., Orth G., Abel L., Prétet JL., Fraitag S., Jouanguy E., Tangye SG., Davis M., Notarangelo LD., Marr N., Waterboer T., Langlais D., Doorbar J., Hovnanian A., Christensen N., Bossuyt X., Shahrooei M. and Casanova JL. Cell 184:3812-3828, 2021. PMID: 34214472
Inherited human c-Rel deficiency disrupts myeloid and lymphoid immunity to various infectious agents.
Lévy, R., Langlais, D., Béziat, V., Rapaport, F., Rao, G., Lazarov, T., Bourge, Zhou, YJ., Briand, C., Moriya, K., Ailal, F., Avery, DT., Markle, J., Lim, AI., Ogishi, M., Yang, R., Pelham, S., Emam, M., MMigaud, M., Deswarte, C., Habib, T., Guennoun, A., Boisson, B., SBelkaya, S., Martinez-Barricarte, R., Rosain, J., Belkadi, A., Breton, S., Payne, K., Benhsaien, I., Plebani, A., Neven, B., Blanche, S., Di Santo, JP., Abel, L., Ma, CS., Aziz Bousfiha, AA., Marr, N., Bustamante, J., Liu, K., Gros, P., Geissmann, F., Tangye, SG., Casanova, JL., and Puel, A.. J. Clin. Investigation 131(17):e150143, 2021. PMID: 34623332
The IL-1 Receptor Is Required to Maintain Neutrophil Viability and Function During Aspergillus fumigatus Airway Infection.
Ralph, BAWR, Lehoux, M, Ostapska, H, Snarr BD, Caffrey-Carr AK, Fraser, R, Saleh, M, Obar, JJ, Qureshi, ST, Sheppard, DC. Front. Immunol. 2021 July. https://doi.org/10.3389/fimmu.2021.675294 PMID: 34322116
Loss of MYSM1 inhibits the oncogenic activity of cMYC in mouse models of B cell lymphoma.
Lin YH, Wang HC, Fiore A, Förster M, Tung J, Belle J, Robert F, Pelletier J, Langlais D, Nijnik A (2021). Journal of Cellular and Molecular Medicine (IF=5.3). 25(14):7089-7094. doi:10.1111/jcmm.16554 PMID: 34114734
A forward genetic screen identifies modifiers of rocaglate responsiveness.
Shen L, Pugsley L, Cencic R, Wang HC, Sahni A, Morin G, Robert F, Nijnik A, Porco JA Jr., Langlais D, Huang S, Pelletier J (2021). Scientific Reports (IF=4.4) 11:18516, doi.org/10.1038/s41598-021-97765-8 PMID: 34531456
Engineering a Potent Cancer Vaccine Using Immunproteasome-Expressing Mesenchymal Stromal Cells.
J. Abusarah, F. Khodayarian, N. El-Hachem, Y. Cui, M. Olivier, M. Balood, K. Roversi, S. Talbot, J.P. Bikorimana, J. Chen, M. Jolicoeur, L. Ramet, L.E. Trudeau, S. Kamyabiazar, B. Annabi, F. Robert, J. Pelletier, A.E. El-Kadiry, R. Shammaa and M. Rafei. Cell Reports Medicine doi.org\10.1016/j.xcm.2021.100455 (2021) PMID: 35028603
A multimodal intervention increases influenza vaccine uptake in rheumatoid arthritis.
Valerio V, Bazan MC, Wang M, Mazer BD, Pineau CA, Hazel EM, Bernatsky S, Ward BJ, Colmegna I. (2021). Clin Rheumatol. 40(2): 575-579. http://dx.doi.org/10.1007/s10067-020-05435-3 PMID: 33030631
3DGV: immersive exploration of 3D genome structures using virtual reality.
Éric Zhang, Christomos Drogaris, Antoine Gédon, Aaron Sossin, Rajae Faraj, Haifen Chen, Yan Cyr, Jacek Majewski, Mathieu Blanchette, and Jérôme Waldispühl. bioRxiv, 2021.
CYRI/FAM49B negatively regulates RAC1-driven cytoskeletal remodelling and protects against bacterial infection.
Yuki KE, Marei H, Fiskin E, Eva MM, Gopal AA, Schwartzentruber JA, Majewski J, Cellier M, Mandl JN, Vidal SM, Malo D, Dikic I.Nat Microbiol.(IF=17.7) 2019 Sep;4(9):1516-1531. PMID: 3128558